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EGFR Inhibitor
CAS No. 879127-07-8
EGFR Inhibitor ( —— )
Catalog No. M19965 CAS No. 879127-07-8
EGFR inhibitor is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 146 | In Stock |
|
| 10MG | 245 | In Stock |
|
| 25MG | 492 | In Stock |
|
| 50MG | 701 | In Stock |
|
| 100MG | 954 | In Stock |
|
| 500MG | 1908 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEGFR Inhibitor
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NoteResearch use only not for human use.
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Brief DescriptionEGFR inhibitor is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.
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DescriptionEGFR inhibitor is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.
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Synonyms——
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR; EGFR (L858R); EGFR (L861Q)
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Research Area——
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Indication——
Chemical Information
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CAS Number879127-07-8
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Formula Weight413.4
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Molecular FormulaC21H18F3N5O
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Purity>98% (HPLC)
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SolubilityDMSO: 25 mg/mL;Ethanol: 10 mg/mL
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SMILESFC(F)(F)c1cccc(Nc2cc(Nc3cccc(NC(=O)C4CC4)c3)ncn2)c1
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Chemical NameN-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhang Q et al. Discovery of EGFR selective 46-disubstituted pyrimidines from a combinatorial kinase-directed heterocycle library. J Am Chem Soc. 2006 Feb 22;128(7):2182-3.
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