Cart
sales@molnova.com
EGFR Inhibitor
CAS No. 879127-07-8
EGFR Inhibitor ( —— )
Catalog No. M19965 CAS No. 879127-07-8
EGFR inhibitor is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 146 | In Stock |
|
| 10MG | 245 | In Stock |
|
| 25MG | 492 | In Stock |
|
| 50MG | 701 | In Stock |
|
| 100MG | 954 | In Stock |
|
| 500MG | 1908 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameEGFR Inhibitor
-
NoteResearch use only not for human use.
-
Brief DescriptionEGFR inhibitor is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.
-
DescriptionEGFR inhibitor is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.
-
Synonyms——
-
PathwayAngiogenesis
-
TargetEGFR
-
RecptorEGFR; EGFR (L858R); EGFR (L861Q)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number879127-07-8
-
Formula Weight413.4
-
Molecular FormulaC21H18F3N5O
-
Purity>98% (HPLC)
-
SolubilityDMSO: 25 mg/mL;Ethanol: 10 mg/mL
-
SMILESFC(F)(F)c1cccc(Nc2cc(Nc3cccc(NC(=O)C4CC4)c3)ncn2)c1
-
Chemical NameN-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Zhang Q et al. Discovery of EGFR selective 46-disubstituted pyrimidines from a combinatorial kinase-directed heterocycle library. J Am Chem Soc. 2006 Feb 22;128(7):2182-3.
molnova catalog
related products
-
Cetuximab (anti-EGFR...
Cetuximab (anti-EGFR) is an inhibitor of epidermal growth factor receptor (EGFR).
-
WHI-P258
WHI-P258 is a dimethoxyquinazoline inhibitor of JAK3.
-
Alflutinib
Alflutinib (AST-2818, ASK120067) is a third generation EGFR mutation selective tyrosine kinase inhibitor.
